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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SAMHD1
All Species:
6.36
Human Site:
S603
Identified Species:
11.67
UniProt:
Q9Y3Z3
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y3Z3
NP_056289.2
626
72201
S603
K
E
W
N
D
S
T
S
V
Q
N
P
T
R
L
Chimpanzee
Pan troglodytes
XP_514624
382
43769
N362
V
S
C
A
R
G
G
N
K
N
I
V
P
G
L
Rhesus Macaque
Macaca mulatta
XP_001097562
728
83194
S705
K
E
W
N
Y
R
T
S
V
Q
S
P
T
R
L
Dog
Lupus familis
XP_542986
665
76981
S642
A
E
W
N
N
M
D
S
A
Q
S
P
D
H
F
Cat
Felis silvestris
Mouse
Mus musculus
Q60710
627
72632
L605
I
A
P
L
I
T
P
L
K
W
N
N
K
T
S
Rat
Rattus norvegicus
XP_230789
677
77635
L655
I
A
P
L
I
T
P
L
K
W
N
K
K
T
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZJL9
614
70202
L586
V
A
P
H
L
T
P
L
K
Q
S
W
N
N
R
Frog
Xenopus laevis
Q6INN8
632
72730
D609
A
S
W
V
D
D
D
D
D
E
D
N
E
G
K
Zebra Danio
Brachydanio rerio
Q502K2
622
71649
D582
Q
D
W
H
A
R
E
D
E
D
E
E
E
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09374
587
66474
Q565
T
P
R
K
R
S
P
Q
D
S
P
D
E
V
S
Sea Urchin
Strong. purpuratus
XP_784786
594
68895
R574
L
D
S
K
K
R
P
R
E
D
E
T
R
T
P
Poplar Tree
Populus trichocarpa
XP_002312899
477
54770
L457
E
A
F
E
N
F
Q
L
N
K
Y
G
I
K
A
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_568580
473
54655
R453
A
F
E
N
F
Q
M
R
T
Y
G
I
K
A
Q
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
58.9
79.5
73.5
N.A.
73.3
65.8
N.A.
N.A.
60
61.8
60.8
N.A.
N.A.
N.A.
22.5
46.8
Protein Similarity:
100
60.2
82.4
83.6
N.A.
83.2
76.2
N.A.
N.A.
74.9
75.3
74.1
N.A.
N.A.
N.A.
40.8
64.2
P-Site Identity:
100
6.6
80
40
N.A.
6.6
6.6
N.A.
N.A.
6.6
13.3
6.6
N.A.
N.A.
N.A.
6.6
0
P-Site Similarity:
100
13.3
86.6
53.3
N.A.
13.3
13.3
N.A.
N.A.
26.6
26.6
26.6
N.A.
N.A.
N.A.
6.6
6.6
Percent
Protein Identity:
28.2
N.A.
N.A.
30.5
N.A.
N.A.
Protein Similarity:
45
N.A.
N.A.
47.2
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
33.3
N.A.
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
24
31
0
8
8
0
0
0
8
0
0
0
0
8
8
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
16
0
0
16
8
16
16
16
16
8
8
8
0
0
% D
% Glu:
8
24
8
8
0
0
8
0
16
8
16
8
24
8
8
% E
% Phe:
0
8
8
0
8
8
0
0
0
0
0
0
0
0
8
% F
% Gly:
0
0
0
0
0
8
8
0
0
0
8
8
0
16
0
% G
% His:
0
0
0
16
0
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
16
0
0
0
16
0
0
0
0
0
8
8
8
0
0
% I
% Lys:
16
0
0
16
8
0
0
0
31
8
0
8
24
8
8
% K
% Leu:
8
0
0
16
8
0
0
31
0
0
0
0
0
0
24
% L
% Met:
0
0
0
0
0
8
8
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
31
16
0
0
8
8
8
24
16
8
8
0
% N
% Pro:
0
8
24
0
0
0
39
0
0
0
8
24
8
0
8
% P
% Gln:
8
0
0
0
0
8
8
8
0
31
0
0
0
0
8
% Q
% Arg:
0
0
8
0
16
24
0
16
0
0
0
0
8
16
8
% R
% Ser:
0
16
8
0
0
16
0
24
0
8
24
0
0
0
24
% S
% Thr:
8
0
0
0
0
24
16
0
8
0
0
8
16
24
0
% T
% Val:
16
0
0
8
0
0
0
0
16
0
0
8
0
8
0
% V
% Trp:
0
0
39
0
0
0
0
0
0
16
0
8
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
0
0
8
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _